T7P (p.Thr7Pro) variant of MAP2K1 (Q02750)
T7P (p.Thr7Pro) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
T7P (p.Thr7Pro) variant details
- p.Thr7Pro
- gnomAD 15-66387366-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- REVEL 0.47
- MetaLR 0.78
- MetaSVM 0.23
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available