T7K (p.Thr7Lys) variant of MAP2K1 (Q02750)
T7K (p.Thr7Lys) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
T7K (p.Thr7Lys) variant details
- p.Thr7Lys
- gnomAD 15-66387367-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.44
- MetaLR 0.77
- MetaSVM 0.18
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available