T23S (p.Thr23Ser) variant of MAP2K1 (Q02750)
T23S (p.Thr23Ser) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
T23S (p.Thr23Ser) variant details
- p.Thr23Ser
- gnomAD 15-66387414-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.34
- MetaLR 0.57
- MetaSVM -0.22
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.47
- Population evidence available
- Structural context available
- Literature evidence available