T23N (p.Thr23Asn) variant of MAP2K1 (Q02750)
T23N (p.Thr23Asn) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
T23N (p.Thr23Asn) variant details
- p.Thr23Asn
- gnomAD 15-66387415-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.35
- MetaLR 0.58
- MetaSVM -0.09
- CADD 21.30
- PolyPhen-2 0.02
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available