T23A (p.Thr23Ala) variant of MAP2K1 (Q02750)
T23A (p.Thr23Ala) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
T23A (p.Thr23Ala) variant details
- p.Thr23Ala
- gnomAD 15-66387414-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.35
- MetaLR 0.55
- MetaSVM -0.26
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.33
- Population evidence available
- Structural context available
- Literature evidence available