S24S (p.Ser24Ser) variant of MAP2K1 (Q02750)
S24S (p.Ser24Ser) in MAP2K1 (Q02750) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S24S (p.Ser24Ser) variant details
- p.Ser24Ser
- gnomAD 15-66387419-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.449
- CADD 15.00
- Population evidence available
- Structural context available
- Dabrafenib and Cetuximab HT-29 cells, base editing z-scores (predicted consequen: score 0.126
- Literature evidence available