P8T (p.Pro8Thr) variant of MAP2K1 (Q02750)
P8T (p.Pro8Thr) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
P8T (p.Pro8Thr) variant details
- p.Pro8Thr
- gnomAD 15-66387369-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.47
- MetaLR 0.64
- MetaSVM 0.38
- CADD 23.40
- PolyPhen-2 0.17
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available