P8S (p.Pro8Ser) variant of MAP2K1 (Q02750)
P8S (p.Pro8Ser) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
P8S (p.Pro8Ser) variant details
- p.Pro8Ser
- gnomAD 15-66387369-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- REVEL 0.43
- MetaLR 0.65
- MetaSVM 0.37
- CADD 23.60
- PolyPhen-2 0.17
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available