P6S (p.Pro6Ser) variant of MAP2K1 (Q02750)
P6S (p.Pro6Ser) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
P6S (p.Pro6Ser) variant details
- p.Pro6Ser
- Ensembl rs2140511627
- Missense
- Variant Prioritization Score for Impact Estimate 0.664
- REVEL 0.56
- MetaLR 0.81
- MetaSVM 0.60
- CADD 25.70
- PolyPhen-2 0.94
- SIFT 0.05
- Population evidence available
- Structural context available