P6L (p.Pro6Leu) variant of MAP2K1 (Q02750)
P6L (p.Pro6Leu) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
P6L (p.Pro6Leu) variant details
- p.Pro6Leu
- gnomAD 15-66387364-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.58
- MetaLR 0.68
- MetaSVM 0.33
- CADD 26.20
- PolyPhen-2 0.66
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available