P2T (p.Pro2Thr) variant of MAP2K1 (Q02750)
P2T (p.Pro2Thr) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
P2T (p.Pro2Thr) variant details
- p.Pro2Thr
- gnomAD 15-66387351-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.32
- MetaLR 0.21
- MetaSVM -0.76
- CADD 23.30
- PolyPhen-2 0.12
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available