P2S (p.Pro2Ser) variant of MAP2K1 (Q02750)
P2S (p.Pro2Ser) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
P2S (p.Pro2Ser) variant details
- p.Pro2Ser
- gnomAD 15-66387351-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.16
- MetaLR 0.19
- MetaSVM -0.89
- CADD 22.50
- PolyPhen-2 0.08
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available