P15T (p.Pro15Thr) variant of MAP2K1 (Q02750)
P15T (p.Pro15Thr) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
P15T (p.Pro15Thr) variant details
- p.Pro15Thr
- gnomAD 15-66387390-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.36
- MetaLR 0.63
- MetaSVM 0.12
- CADD 22.00
- PolyPhen-2 0.06
- SIFT 0.30
- Population evidence available
- Structural context available
- Literature evidence available