P13L (p.Pro13Leu) variant of MAP2K1 (Q02750)
P13L (p.Pro13Leu) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
P13L (p.Pro13Leu) variant details
- p.Pro13Leu
- gnomAD 15-66387385-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.692
- REVEL 0.61
- MetaLR 0.86
- MetaSVM 0.75
- CADD 24.50
- PolyPhen-2 0.65
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available