N21S (p.Asn21Ser) variant of MAP2K1 (Q02750)
N21S (p.Asn21Ser) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
N21S (p.Asn21Ser) variant details
- p.Asn21Ser
- gnomAD 15-66387409-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.38
- MetaLR 0.55
- MetaSVM -0.17
- CADD 22.40
- PolyPhen-2 0.08
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available