N21D (p.Asn21Asp) variant of MAP2K1 (Q02750)
N21D (p.Asn21Asp) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
N21D (p.Asn21Asp) variant details
- p.Asn21Asp
- gnomAD 15-66387408-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.41
- MetaLR 0.55
- MetaSVM 0.05
- CADD 23.20
- PolyPhen-2 0.14
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available