K5M (p.Lys5Met) variant of MAP2K1 (Q02750)
K5M (p.Lys5Met) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
K5M (p.Lys5Met) variant details
- p.Lys5Met
- gnomAD 15-66387361-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.695
- REVEL 0.71
- MetaLR 0.78
- MetaSVM 0.65
- CADD 28.30
- PolyPhen-2 0.81
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available