K5E (p.Lys5Glu) variant of MAP2K1 (Q02750)
K5E (p.Lys5Glu) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
K5E (p.Lys5Glu) variant details
- p.Lys5Glu
- gnomAD 15-66387360-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.60
- MetaLR 0.63
- MetaSVM 0.27
- CADD 24.60
- PolyPhen-2 0.18
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available