K4K (p.Lys4Lys) variant of MAP2K1 (Q02750)
K4K (p.Lys4Lys) in MAP2K1 (Q02750) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
K4K (p.Lys4Lys) variant details
- p.Lys4Lys
- rs1489477346
- gnomAD 15-66387359-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.54
- CADD 13.80
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available