K4E (p.Lys4Glu) variant of MAP2K1 (Q02750)
K4E (p.Lys4Glu) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
K4E (p.Lys4Glu) variant details
- p.Lys4Glu
- gnomAD 15-66387357-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- REVEL 0.46
- MetaLR 0.65
- MetaSVM 0.18
- CADD 24.40
- PolyPhen-2 0.07
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available