K3T (p.Lys3Thr) variant of MAP2K1 (Q02750)
K3T (p.Lys3Thr) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
K3T (p.Lys3Thr) variant details
- p.Lys3Thr
- gnomAD 15-66387355-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.43
- MetaLR 0.52
- MetaSVM -0.03
- CADD 24.20
- PolyPhen-2 0.18
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available