K3M (p.Lys3Met) variant of MAP2K1 (Q02750)
K3M (p.Lys3Met) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
K3M (p.Lys3Met) variant details
- p.Lys3Met
- gnomAD 15-66387355-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.651
- REVEL 0.64
- MetaLR 0.77
- MetaSVM 0.55
- CADD 27.30
- PolyPhen-2 0.67
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available