K3E (p.Lys3Glu) variant of MAP2K1 (Q02750)
K3E (p.Lys3Glu) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
K3E (p.Lys3Glu) variant details
- p.Lys3Glu
- gnomAD 15-66387354-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.45
- MetaLR 0.72
- MetaSVM 0.35
- CADD 24.40
- PolyPhen-2 0.07
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available