G22R (p.Gly22Arg) variant of MAP2K1 (Q02750)
G22R (p.Gly22Arg) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- gnomAD 15-66387411-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.50
- MetaLR 0.58
- MetaSVM 0.05
- CADD 23.20
- PolyPhen-2 0.25
- SIFT 0.35
- Population evidence available
- Structural context available
- Literature evidence available