G17S (p.Gly17Ser) variant of MAP2K1 (Q02750)
G17S (p.Gly17Ser) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
G17S (p.Gly17Ser) variant details
- p.Gly17Ser
- gnomAD 15-66387396-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.48
- MetaLR 0.64
- MetaSVM 0.18
- CADD 23.20
- PolyPhen-2 0.36
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available