G17R (p.Gly17Arg) variant of MAP2K1 (Q02750)
G17R (p.Gly17Arg) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- gnomAD rs1157933155
- Missense
- Variant Prioritization Score for Impact Estimate 0.696
- REVEL 0.63
- MetaLR 0.80
- MetaSVM 0.52
- CADD 27.50
- PolyPhen-2 0.87
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available