G17C (p.Gly17Cys) variant of MAP2K1 (Q02750)
G17C (p.Gly17Cys) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
G17C (p.Gly17Cys) variant details
- p.Gly17Cys
- gnomAD 15-66387396-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.55
- MetaLR 0.65
- MetaSVM 0.36
- CADD 28.70
- PolyPhen-2 0.92
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available