A14G (p.Ala14Gly) variant of MAP2K1 (Q02750)
A14G (p.Ala14Gly) in MAP2K1 (Q02750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A14G (p.Ala14Gly) variant details
- p.Ala14Gly
- gnomAD 15-66387388-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.28
- MetaLR 0.55
- MetaSVM -0.15
- CADD 22.70
- PolyPhen-2 0.02
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available