Y60C (p.Tyr60Cys) variant of MAOB (P27338)
Y60C (p.Tyr60Cys) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
Y60C (p.Tyr60Cys) variant details
- p.Tyr60Cys
- ESP rs370820554
- TOPMed rs370820554
- gnomAD rs370820554
- Missense
- Variant Prioritization Score for Impact Estimate 0.805
- REVEL 0.94
- MetaLR 0.89
- MetaSVM 0.99
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 9.8e-05)
- Structural context available