W135* (p.Trp135Ter) variant of MAOB (P27338)
W135* (p.Trp135Ter) in MAOB (P27338) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
W135* (p.Trp135Ter) variant details
- p.Trp135Ter
- NCI-TCGA Cosmic COSV1009
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.796
- CADD 39.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available