T174N (p.Thr174Asn) variant of MAOB (P27338)
T174N (p.Thr174Asn) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T174N (p.Thr174Asn) variant details
- p.Thr174Asn
- TOPMed rs1459914959
- gnomAD rs1459914959
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.29
- MetaLR 0.11
- MetaSVM -0.94
- CADD 24.50
- PolyPhen-2 0.97
- SIFT 0.19
- Most common in the East Asian population (allele frequency 0.0001)
- Structural context available