S160C (p.Ser160Cys) variant of MAOB (P27338)
S160C (p.Ser160Cys) in MAOB (P27338) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
S160C (p.Ser160Cys) variant details
- p.Ser160Cys
- rs371973652
- NCI-TCGA Cosmic COSV1009
- TOPMed rs371973652
- gnomAD rs371973652
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.43
- MetaLR 0.73
- MetaSVM 0.33
- CADD 20.50
- PolyPhen-2 0.01
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 3.9e-05)
- Structural context available