P63S (p.Pro63Ser) variant of MAOB (P27338)
P63S (p.Pro63Ser) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
P63S (p.Pro63Ser) variant details
- p.Pro63Ser
- TOPMed rs1298437740
- gnomAD rs1298437740
- Missense
- Variant Prioritization Score for Impact Estimate 0.739
- REVEL 0.80
- MetaLR 0.87
- MetaSVM 0.84
- CADD 24.20
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available