L69W (p.Leu69Trp) variant of MAOB (P27338)
L69W (p.Leu69Trp) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
L69W (p.Leu69Trp) variant details
- p.Leu69Trp
- Ensembl rs2035101263
- Missense
- Variant Prioritization Score for Impact Estimate 0.786
- REVEL 0.90
- MetaLR 0.90
- MetaSVM 0.96
- CADD 25.60
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 0.00067)
- Structural context available