K154N (p.Lys154Asn) variant of MAOB (P27338)
K154N (p.Lys154Asn) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
K154N (p.Lys154Asn) variant details
- p.Lys154Asn
- ExAC rs774808110
- TOPMed rs774808110
- gnomAD rs774808110
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.13
- MetaLR 0.03
- MetaSVM -1.09
- CADD 21.70
- PolyPhen-2 0.14
- SIFT 0.03
- Most common in the Ashkenazi Jewish population (allele frequency 5.2e-05)
- Structural context available