I221M (p.Ile221Met) variant of MAOB (P27338)
I221M (p.Ile221Met) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
I221M (p.Ile221Met) variant details
- p.Ile221Met
- ExAC rs761533542
- gnomAD rs761533542
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.10
- MetaLR 0.01
- MetaSVM -0.90
- CADD 14.90
- PolyPhen-2 0.14
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available