G58R (p.Gly58Arg) variant of MAOB (P27338)
G58R (p.Gly58Arg) in MAOB (P27338) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data and structural context.
G58R (p.Gly58Arg) variant details
- p.Gly58Arg
- NCI-TCGA TCGA novel
- NCI-TCGA Cosmic COSV1009
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.868
- REVEL 0.97
- MetaLR 0.92
- MetaSVM 1.08
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available