G226E (p.Gly226Glu) variant of MAOB (P27338)
G226E (p.Gly226Glu) in MAOB (P27338) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G226E (p.Gly226Glu) variant details
- p.Gly226Glu
- NCI-TCGA TCGA novel
- gnomAD rs2034520856
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.21
- MetaLR 0.09
- MetaSVM -1.03
- CADD 22.80
- PolyPhen-2 0.53
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00067)
- Structural context available