G213R (p.Gly213Arg) variant of MAOB (P27338)
G213R (p.Gly213Arg) in MAOB (P27338) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G213R (p.Gly213Arg) variant details
- p.Gly213Arg
- NCI-TCGA Cosmic COSV6520
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- REVEL 0.66
- MetaLR 0.29
- MetaSVM -0.15
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available