E159D (p.Glu159Asp) variant of MAOB (P27338)
E159D (p.Glu159Asp) in MAOB (P27338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
E159D (p.Glu159Asp) variant details
- p.Glu159Asp
- ExAC rs766994984
- TOPMed rs766994984
- gnomAD rs766994984
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.18
- MetaLR 0.50
- MetaSVM -0.55
- CADD 12.50
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 6.5e-05)
- Structural context available