V36A (p.Val36Ala) variant of LRRK2 (Q5S007)
V36A (p.Val36Ala) in LRRK2 (Q5S007) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V36A (p.Val36Ala) variant details
- p.Val36Ala
- TOPMed rs1371271059
- gnomAD rs1371271059
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.10
- MetaLR 0.08
- MetaSVM -0.84
- CADD 24.40
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available