T46T (p.Thr46Thr) variant of LRRK2 (Q5S007)
T46T (p.Thr46Thr) in LRRK2 (Q5S007) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
T46T (p.Thr46Thr) variant details
- p.Thr46Thr
- rs1036182021
- gnomAD 12-40225269-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.107
- CADD 3.73
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available