S48S (p.Ser48Ser) variant of LRRK2 (Q5S007)
S48S (p.Ser48Ser) in LRRK2 (Q5S007) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
S48S (p.Ser48Ser) variant details
- p.Ser48Ser
- gnomAD 12-40225275-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.163
- CADD 11.60
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available