R22R (p.Arg22Arg) variant of LRRK2 (Q5S007)
R22R (p.Arg22Arg) in LRRK2 (Q5S007) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
R22R (p.Arg22Arg) variant details
- p.Arg22Arg
- rs151283507
- gnomAD 12-40225197-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.277
- CADD 13.60
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available