Q27R (p.Gln27Arg) variant of LRRK2 (Q5S007)
Q27R (p.Gln27Arg) in LRRK2 (Q5S007) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Q27R (p.Gln27Arg) variant details
- p.Gln27Arg
- gnomAD rs1347707737
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.17
- MetaLR 0.13
- MetaSVM -0.77
- CADD 26.60
- PolyPhen-2 0.63
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available