N24D (p.Asn24Asp) variant of LRRK2 (Q5S007)
N24D (p.Asn24Asp) in LRRK2 (Q5S007) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
N24D (p.Asn24Asp) variant details
- p.Asn24Asp
- gnomAD 12-40225201-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.04
- CADD 23.80
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available
- Literature evidence available