L65D (p.Leu65Asp) variant of LRRK2 (Q5S007)
L65D (p.Leu65Asp) in LRRK2 (Q5S007) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data, published literature, and structural context.
L65D (p.Leu65Asp) variant details
- p.Leu65Asp
- rs1181905113
- gnomAD 12-40225593-CTG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.708
- CADD 31.00
- Population evidence available
- Structural context available
- Literature evidence available