K58Q (p.Lys58Gln) variant of LRRK2 (Q5S007)
K58Q (p.Lys58Gln) in LRRK2 (Q5S007) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
K58Q (p.Lys58Gln) variant details
- p.Lys58Gln
- gnomAD 12-40225575-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.12
- MetaLR 0.09
- MetaSVM -1.02
- CADD 22.90
- PolyPhen-2 0.04
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available