I60V (p.Ile60Val) variant of LRRK2 (Q5S007)
I60V (p.Ile60Val) in LRRK2 (Q5S007) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
I60V (p.Ile60Val) variant details
- p.Ile60Val
- gnomAD 12-40225581-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -0.98
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available