G57G (p.Gly57Gly) variant of LRRK2 (Q5S007)
G57G (p.Gly57Gly) in LRRK2 (Q5S007) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
G57G (p.Gly57Gly) variant details
- p.Gly57Gly
- gnomAD 12-40225574-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.276
- CADD 15.50
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available
- Literature evidence available